Entrepreneurship in Pirot has a long tradition and represents a developmental opportunity to employ people who have lost their jobs in the period of transition and structural adjustment of the economy. The number of active entrepreneurs in October 2020 was 1500. According to 2022 data, entrepreneurs and employees are 2,941.
Sectoral affiliation of entrepreneurial shops in Pirot
| Sector | Number | Percentage |
| Wholesale and retail trade | 315 | 20,1 |
| Manufacturing sector | 301 | 19,2 |
| Other service activities | 143 | 9,1 |
| Traffic and storage | 166 | 10,6 |
| Professional, scientific innovation and technical activities | 127 | 8,1 |
| Construction | 117 | 7,4 |
| Accommodation and food services | 117 | 7,4 |
| Other | 285 | 18,1 |
| Total: | 1571 | 100 |
Looking at entrepreneurial actions according to sectoral affiliation, it is realized that the trade sector includes the largest number of entrepreneurs, followed by the manufacturing sector, while their participation in other sectors is much smaller.
Strategija održivog razvoja opštine Pirot.
Postupak izdavanja odobrenja za izgradnju industrijskog objekta za koji odobrenje izdaje opštinska, odnosno gradska uprava.
